| 9/3/2016 | Southern Connecticut (6-5) | 9 | at | Gannon | 31 | NE10 | ||
| 9/10/2016 | Gannon | 24 | at | Shippensburg (7-4,6-4) | 20 | |||
| 9/17/2016 | Bloomsburg (6-5,5-5) | 27 | at | Gannon | 30 | OT | ||
| 9/24/2016 | Gannon | 13 | at | Slippery Rock (7-4,6-4) | 34 | |||
| 10/1/2016 | Mercyhurst (3-8,3-7) | 38 | at | Gannon | 35 | OT | ||
| 10/8/2016 | Gannon | 17 | at | Edinboro (9-2,8-2) | 41 | |||
| 10/15/2016 | Seton Hill (5-6,4-6) | 12 | at | Gannon | 34 | |||
| 10/22/2016 | Gannon | 14 | at | California PA (11-1,11-0) | 35 | |||
| 10/29/2016 | Indiana PA (10-2,9-2) | 48 | at | Gannon | 3 | |||
| 11/5/2016 | Gannon | 35 | at | Clarion (4-7,4-7) | 41 | |||
| 11/12/2016 | Millersville (2-9,1-9) | 14 | at | Gannon | 31 |
| vs Gannon | vs Other Opponents | Gannon compared to OOs | |
| Record: | 6-5 | 64-48 | |
| Points Scored: | 29.00 | 32.90 | 3.90 |
| Points Allowed: | 24.27 | 28.50 | -4.23 |
| Margin: | 4.73 | 4.40 | -0.33 |
| Total Points: | 53.27 | 61.40 | -8.13 |