| 9/3/2016 | Eastern Washington | 45 | at | Washington State (8-5) | 42 | at P12 | ||
| 9/10/2016 | Eastern Washington | 44 | at | North Dakota State (12-2) | 50 | OT | at MVC | |
| 9/17/2016 | Northern Iowa (5-6) | 30 | at | Eastern Washington | 34 | MVC | ||
| 9/24/2016 | Eastern Washington | 50 | at | Northern Arizona (5-6,4-4) | 35 | |||
| 10/1/2016 | UC Davis (3-8,2-6) | 30 | at | Eastern Washington | 63 | |||
| 10/8/2016 | Northern Colorado (6-5,4-4) | 31 | at | Eastern Washington | 49 | |||
| 10/22/2016 | Eastern Washington | 41 | at | Montana State (4-7,2-6) | 17 | |||
| 10/29/2016 | Montana (6-5,3-5) | 16 | at | Eastern Washington | 35 | |||
| 11/5/2016 | Eastern Washington | 42 | at | Cal Poly (7-5,5-3) | 21 | |||
| 11/12/2016 | Idaho State (2-9,1-7) | 17 | at | Eastern Washington | 48 | |||
| 11/18/2016 | Eastern Washington | 35 | at | Portland State (3-8,2-6) | 28 | |||
| 12/3/2016 | Central Arkansas (10-3) | 14 | at | Eastern Washington | 31 | 1AA Playoffs | SLC | |
| 12/10/2016 | Richmond (10-4) | 0 | at | Eastern Washington | 38 | 1AA Quarterfinals | CAAF | |
| 12/17/2016 | Youngstown State (12-4) | 40 | at | Eastern Washington | 38 | 1AA Semifinal | MVC |
| vs Eastern Washington | vs Other Opponents | Eastern Washington compared to OOs | |
| Record: | 2-12 | 91-65 | |
| Points Scored: | 26.50 | 31.65 | 5.15 |
| Points Allowed: | 42.36 | 26.40 | 15.96 |
| Margin: | -15.86 | 5.25 | 21.11 |
| Total Points: | 68.86 | 58.05 | 10.81 |