| 9/6/2015 | Alabama State (6-5) | 14 | at | Tennessee State | 24 | SWAC | ||
| 9/12/2015 | Jackson State (3-8) | 25 | vs | Tennessee State | 35 | Memphis TN | SWAC | |
| 9/19/2015 | Tennessee State | 13 | at | Jacksonville State (13-2,8-0) | 48 | |||
| 9/26/2015 | Tennessee State | 30 | at | Florida A&M (1-10) | 14 | at MEAC | ||
| 10/10/2015 | Tennessee State | 14 | at | Tennessee-Martin (7-4,6-2) | 28 | |||
| 10/17/2015 | Eastern Illinois (7-5,7-1) | 25 | at | Tennessee State | 22 | OT | ||
| 10/24/2015 | Tennessee State | 21 | at | Eastern Kentucky (6-5,5-3) | 45 | |||
| 10/31/2015 | Austin Peay (0-11,0-8) | 6 | at | Tennessee State | 20 | |||
| 11/7/2015 | Murray State (3-8,2-6) | 46 | at | Tennessee State | 43 | OT | ||
| 11/21/2015 | Tennessee State | 24 | at | Tennessee Tech (4-7,3-5) | 30 |
| vs Tennessee State | vs Other Opponents | Tennessee State compared to OOs | |
| Record: | 6-4 | 44-61 | |
| Points Scored: | 28.10 | 25.92 | -2.18 |
| Points Allowed: | 24.60 | 30.91 | -6.31 |
| Margin: | 3.50 | -4.99 | -8.49 |
| Total Points: | 52.70 | 56.83 | -4.13 |