| 9/5/2015 | Tennessee-Martin (7-4) | 3 | at | Mississippi | 76 | OVC (1AA) | ||
| 9/12/2015 | Fresno State (3-9) | 21 | at | Mississippi | 73 | MW | ||
| 9/19/2015 | Mississippi | 43 | at | Alabama (14-1,8-1) | 37 | |||
| 9/26/2015 | Vanderbilt (4-8,2-6) | 17 | at | Mississippi | 26 | |||
| 10/3/2015 | Mississippi | 10 | at | Florida (10-4,7-2) | 38 | |||
| 10/10/2015 | New Mexico State (3-9) | 3 | at | Mississippi | 52 | SBC | ||
| 10/17/2015 | Mississippi | 24 | at | Memphis (9-4) | 37 | at AAC | ||
| 10/24/2015 | Texas A&M (8-5,4-4) | 3 | at | Mississippi | 23 | |||
| 10/31/2015 | Mississippi | 27 | at | Auburn (7-6,2-6) | 19 | |||
| 11/7/2015 | Arkansas (8-5,5-3) | 53 | at | Mississippi | 52 | OT | ||
| 11/21/2015 | LSU (9-3,5-3) | 17 | at | Mississippi | 38 | |||
| 11/28/2015 | Mississippi | 38 | at | Mississippi State (9-4,4-4) | 27 | |||
| 1/1/2016 | Oklahoma State (10-3) | 20 | vs | Mississippi | 48 | Sugar Bowl (New Orleans LA) | B12 |
| vs Mississippi | vs Other Opponents | Mississippi compared to OOs | |
| Record: | 3-10 | 98-55 | |
| Points Scored: | 22.69 | 31.33 | 8.64 |
| Points Allowed: | 40.77 | 25.37 | 15.40 |
| Margin: | -18.08 | 5.96 | 24.04 |
| Total Points: | 63.46 | 56.70 | 6.76 |