| 9/5/2015 | Alabama A&M (4-7) | 10 | at | Cincinnati | 52 | SWAC (1AA) | ||
| 9/12/2015 | Temple (10-4,7-2) | 34 | at | Cincinnati | 26 | |||
| 9/19/2015 | Cincinnati | 37 | at | Miami-Ohio (3-9) | 33 | at MAC | ||
| 9/24/2015 | Cincinnati | 46 | at | Memphis (9-4,5-3) | 53 | |||
| 10/1/2015 | Miami-Florida (8-5) | 23 | at | Cincinnati | 34 | ACC | ||
| 10/16/2015 | Cincinnati | 24 | at | BYU (9-4) | 38 | at Ind | ||
| 10/24/2015 | Connecticut (6-7,4-4) | 13 | at | Cincinnati | 37 | |||
| 10/31/2015 | UCF (0-12,0-8) | 7 | at | Cincinnati | 52 | |||
| 11/7/2015 | Cincinnati | 30 | at | Houston (13-1,8-1) | 33 | |||
| 11/14/2015 | Tulsa (6-7,3-5) | 38 | at | Cincinnati | 49 | |||
| 11/20/2015 | Cincinnati | 27 | at | South Florida (8-5,6-2) | 65 | |||
| 11/28/2015 | Cincinnati | 19 | at | East Carolina (5-7,3-5) | 16 | |||
| 12/24/2015 | San Diego State (11-3) | 42 | vs | Cincinnati | 7 | Hawaii Bowl (Honolulu HI) | MW |
| vs Cincinnati | vs Other Opponents | Cincinnati compared to OOs | |
| Record: | 6-7 | 86-68 | |
| Points Scored: | 31.15 | 28.79 | -2.36 |
| Points Allowed: | 33.85 | 25.84 | 8.01 |
| Margin: | -2.70 | 2.95 | 5.65 |
| Total Points: | 65.00 | 54.63 | 10.37 |