| 9/3/2010 | Arizona | 41 | @ | Toledo | 2 | ||||
| 9/11/2010 | The Citadel 1AA | 6 | @ | Arizona | 52 | ||||
| 9/18/2010 | Iowa | 27 | @ | Arizona | 34 | ||||
| 9/25/2010 | California | 9 | @ | Arizona | 10 | P10 | |||
| 10/9/2010 | Oregon State | 29 | @ | Arizona | 27 | P10 | |||
| 10/16/2010 | Arizona | 24 | @ | Washington State | 7 | P10 | |||
| 10/23/2010 | Washington | 14 | @ | Arizona | 44 | P10 | |||
| 10/30/2010 | Arizona | 29 | @ | UCLA | 21 | P10 | |||
| 11/6/2010 | Arizona | 17 | @ | Stanford | 42 | P10 | |||
| 11/13/2010 | Southern California | 24 | @ | Arizona | 21 | P10 | |||
| 11/26/2010 | Arizona | 27 | @ | Oregon | 50 | P10 | |||
| 12/2/2010 | Arizona State | 30 | @ | Arizona | 29 | 2 OT | P10 | ||
| 12/29/2010 | Oklahoma State | 36 | vs | Arizona | 10 | San Antonio - Alamo Bowl |