| 9/4/2010 | Portland State 1AA | 9 | @ | Arizona State | 54 | ||||
| 9/11/2010 | Northern Arizona 1AA | 20 | @ | Arizona State | 41 | ||||
| 9/18/2010 | Arizona State | 19 | @ | Wisconsin | 20 | ||||
| 9/25/2010 | Oregon | 42 | @ | Arizona State | 31 | P10 | |||
| 10/2/2010 | Arizona State | 28 | @ | Oregon State | 31 | P10 | |||
| 10/9/2010 | Arizona State | 24 | @ | Washington | 14 | P10 | |||
| 10/23/2010 | Arizona State | 17 | @ | California | 50 | P10 | |||
| 10/30/2010 | Washington State | 0 | @ | Arizona State | 42 | P10 | |||
| 11/6/2010 | Arizona State | 33 | @ | Southern California | 34 | P10 | |||
| 11/13/2010 | Stanford | 17 | @ | Arizona State | 13 | P10 | |||
| 11/26/2010 | UCLA | 34 | @ | Arizona State | 55 | P10 | |||
| 12/2/2010 | Arizona State | 30 | @ | Arizona | 29 | 2 OT | P10 |