| 9/3/2009 | Kentucky Wesleyan D2 | 10 | @ | Murray St | 66 | ||||
| 9/12/2009 | Murray St | 7 | @ | North Carolina St | 65 | ||||
| 9/19/2009 | Murray St | 10 | @ | Missouri State | 35 | ||||
| 9/26/2009 | Eastern Kentucky | 23 | @ | Murray St | 13 | OVC | |||
| 10/10/2009 | Jacksonville St | 41 | @ | Murray St | 7 | OVC | |||
| 10/17/2009 | Murray St | 9 | @ | Tennessee St | 6 | OVC | |||
| 10/24/2009 | Murray St | 24 | @ | Tennessee-Martin | 38 | OVC | |||
| 10/31/2009 | Eastern Illinois | 16 | @ | Murray St | 10 | OVC | |||
| 11/7/2009 | Austin Peay | 17 | @ | Murray St | 27 | OVC | |||
| 11/14/2009 | Murray St | 13 | @ | SE Missouri St | 49 | OVC | |||
| 11/21/2009 | Murray St | 14 | @ | Tennessee Tech | 45 | OVC |