| 9/5/2009 | Missouri State | 10 | vs | Arkansas | 48 | Little Rock AR | |||
| 9/12/2009 | Tennessee-Martin | 14 | @ | Missouri State | 24 | ||||
| 9/19/2009 | Murray St | 10 | @ | Missouri State | 35 | ||||
| 9/26/2009 | Northern Iowa | 35 | @ | Missouri State | 7 | MVC | |||
| 10/3/2009 | Missouri State | 17 | @ | Youngstown St | 7 | MVC | |||
| 10/10/2009 | S Dakota St | 24 | @ | Missouri State | 17 | MVC | |||
| 10/17/2009 | Missouri State | 17 | @ | Western Illinois | 16 | MVC | |||
| 10/24/2009 | Missouri State | 21 | @ | N Dakota St | 17 | MVC | |||
| 10/31/2009 | Illinois St | 24 | @ | Missouri State | 14 | MVC | |||
| 11/7/2009 | Indiana St | 7 | @ | Missouri State | 31 | MVC | |||
| 11/14/2009 | Missouri State | 24 | @ | Southern Illinois | 44 | MVC |