| 9/3/2009 | Eastern Kentucky | 13 | @ | Indiana | 19 | ||||
| 9/19/2009 | Tennessee Tech | 7 | @ | Eastern Kentucky | 17 | OVC | |||
| 9/26/2009 | Eastern Kentucky | 23 | @ | Murray St | 13 | OVC | |||
| 10/3/2009 | Eastern Kentucky | 36 | @ | Eastern Illinois | 31 | OVC | |||
| 10/10/2009 | Tennessee St | 20 | @ | Eastern Kentucky | 17 | OVC | |||
| 10/17/2009 | Tennessee-Martin | 25 | @ | Eastern Kentucky | 31 | OVC | |||
| 10/24/2009 | Eastern Kentucky | 20 | @ | Austin Peay | 24 | OVC | |||
| 10/31/2009 | SE Missouri St | 6 | @ | Eastern Kentucky | 20 | OVC | |||
| 11/7/2009 | Eastern Kentucky | 12 | @ | Kentucky | 37 | ||||
| 11/14/2009 | Western Carolina | 24 | @ | Eastern Kentucky | 7 | ||||
| 11/21/2009 | Eastern Kentucky | 26 | @ | Jacksonville St | 34 | OVC |