| 8/24/2024 | Florida State | 21 | vs | Georgia Tech | 24 | Dublin IE | ||
| SMU | 29 | at | Nevada | 24 | @ MW | |||
| 8/29/2024 | North Carolina | 19 | at | Minnesota | 17 | @ B10 | ||
| Western Carolina | 21 | at | North Carolina State | 38 | SoCon (1AA) | |||
| North Carolina A&T | 13 | at | Wake Forest | 45 | CAAF (1AA) | |||
| 8/30/2024 | Elon | 3 | at | Duke | 26 | CAAF (1AA) | ||
| TCU | 34 | at | Stanford | 27 | B12 | |||
| 8/31/2024 | UC Davis | 13 | at | California | 31 | BSky (1AA) | ||
| Miami-Florida | 41 | at | Florida | 17 | @ SEC | |||
| Clemson | 3 | vs | Georgia | 34 | Atlanta GA | vs SEC | ||
| Georgia State | 12 | at | Georgia Tech | 35 | SBC | |||
| Austin Peay | 0 | at | Louisville | 62 | UAC (1AA) | |||
| Kent State | 24 | at | Pittsburgh | 55 | MAC | |||
| Houston Baptist | 7 | at | SMU | 59 | SLC (1AA) | |||
| Ohio | 22 | at | Syracuse | 38 | MAC | |||
| Virginia Tech | 27 | at | Vanderbilt | 34 | @ SEC | |||
| Richmond | 13 | at | Virginia | 34 | CAAF (1AA) | |||
| 9/2/2024 | Boston College | 28 | at | Florida State | 13 | |||
| 9/6/2024 | Duke | 26 | at | Northwestern | 20 | @ B10 | ||
| BYU | 18 | at | SMU | 15 | B12 | |||
| 9/7/2024 | California | 21 | at | Auburn | 14 | @ SEC | ||
| Duquesne | 0 | at | Boston College | 56 | NE (1AA) | |||
| Pittsburgh | 28 | at | Cincinnati | 27 | @ B12 | |||
| Appalachian State | 20 | at | Clemson | 66 | SBC | |||
| Jacksonville State | 14 | at | Louisville | 49 | CUSA | |||
| Florida A&M | 9 | at | Miami-Florida | 56 | SWAC (1AA) | |||
| UNC-Charlotte | 20 | at | North Carolina | 38 | AAC | |||
| Tennessee | 51 | vs | North Carolina State | 10 | Charlotte NC | vs SEC | ||
| Cal Poly | 7 | at | Stanford | 41 | BSky (1AA) | |||
| Georgia Tech | 28 | at | Syracuse | 31 | ||||
| Marshall | 14 | at | Virginia Tech | 31 | SBC | |||
| Virginia | 31 | at | Wake Forest | 30 | ||||
| 9/14/2024 | San Diego State | 10 | at | California | 31 | MW | ||
| Connecticut | 21 | at | Duke | 26 | Ind | |||
| Memphis | 20 | at | Florida State | 12 | AAC | |||
| VMI | 7 | at | Georgia Tech | 59 | SoCon (1AA) | |||
| Ball State | 0 | at | Miami-Florida | 62 | MAC | |||
| Boston College | 21 | at | Missouri | 27 | @ SEC | |||
| North Carolina Central | 10 | at | North Carolina | 45 | MEAC (1AA) | |||
| Louisiana Tech | 20 | at | North Carolina State | 30 | CUSA | |||
| Virginia Tech | 37 | at | Old Dominion | 17 | @ SBC | |||
| West Virginia | 34 | at | Pittsburgh | 38 | B12 | |||
| Maryland | 27 | at | Virginia | 13 | B10 | |||
| Mississippi | 40 | at | Wake Forest | 6 | SEC | |||
| 9/20/2024 | Stanford | 26 | at | Syracuse | 24 | |||
| 9/21/2024 | Michigan State | 19 | at | Boston College | 23 | B10 | ||
| North Carolina State | 35 | at | Clemson | 59 | ||||
| Virginia | 43 | at | Coastal Carolina | 24 | @ SBC | |||
| California | 9 | at | Florida State | 14 | ||||
| Georgia Tech | 19 | at | Louisville | 31 | ||||
| Duke | 45 | at | Middle Tenn State | 17 | @ CUSA | |||
| James Madison | 70 | at | North Carolina | 50 | SBC | |||
| Youngstown State | 17 | at | Pittsburgh | 73 | MVC (1AA) | |||
| TCU | 42 | at | SMU | 66 | B12 | |||
| Miami-Florida | 50 | at | South Florida | 15 | @ AAC | |||
| Rutgers | 26 | at | Virginia Tech | 23 | B10 | |||
| 9/27/2024 | Virginia Tech | 34 | at | Miami-Florida | 38 | |||
| 9/28/2024 | Western Kentucky | 20 | at | Boston College | 21 | CUSA | ||
| Stanford | 14 | at | Clemson | 40 | ||||
| North Carolina | 20 | at | Duke | 21 | ||||
| Northern Illinois | 17 | at | North Carolina State | 24 | MAC | |||
| Louisville | 24 | at | Notre Dame | 31 | @ ND | |||
| Florida State | 16 | at | SMU | 42 | ||||
| Holy Cross | 14 | at | Syracuse | 42 | Pat (1AA) | |||
| UL Lafayette | 41 | at | Wake Forest | 38 | SBC | |||
| 10/4/2024 | Syracuse | 44 | at | UNLV | 41 | @ MW | ||
| 10/5/2024 | Miami-Florida | 39 | at | California | 38 | |||
| Clemson | 29 | at | Florida State | 13 | ||||
| Duke | 14 | at | Georgia Tech | 24 | ||||
| SMU | 34 | at | Louisville | 27 | ||||
| Pittsburgh | 34 | at | North Carolina | 24 | ||||
| Wake Forest | 34 | at | North Carolina State | 30 | ||||
| Virginia Tech | 31 | at | Stanford | 7 | ||||
| Boston College | 14 | at | Virginia | 24 | ||||
| 10/12/2024 | Georgia Tech | 41 | at | North Carolina | 34 | |||
| Syracuse | 24 | at | North Carolina State | 17 | ||||
| Stanford | 7 | at | Notre Dame | 49 | @ ND | |||
| California | 15 | at | Pittsburgh | 17 | ||||
| Louisville | 24 | at | Virginia | 20 | ||||
| Clemson | 49 | at | Wake Forest | 14 | ||||
| 10/17/2024 | Boston College | 21 | at | Virginia Tech | 42 | |||
| 10/18/2024 | Florida State | 16 | at | Duke | 23 | |||
| 10/19/2024 | North Carolina State | 24 | at | California | 23 | |||
| Virginia | 31 | at | Clemson | 48 | ||||
| Wake Forest | 23 | at | Connecticut | 20 | @ Ind | |||
| Notre Dame | 31 | at | Georgia Tech | 13 | ND | |||
| Miami-Florida | 52 | at | Louisville | 45 | ||||
| SMU | 40 | at | Stanford | 10 | ||||
| 10/24/2024 | Syracuse | 13 | at | Pittsburgh | 41 | |||
| 10/25/2024 | Louisville | 31 | at | Boston College | 27 | |||
| 10/26/2024 | Oregon State | 7 | at | California | 44 | P12 | ||
| SMU | 28 | at | Duke | 27 | OT | |||
| Florida State | 14 | at | Miami-Florida | 36 | ||||
| Wake Forest | 27 | at | Stanford | 24 | ||||
| North Carolina | 41 | at | Virginia | 14 | ||||
| Georgia Tech | 6 | at | Virginia Tech | 21 | ||||
| 11/2/2024 | Louisville | 33 | at | Clemson | 21 | |||
| North Carolina | 35 | at | Florida State | 11 | ||||
| Duke | 31 | at | Miami-Florida | 53 | ||||
| Stanford | 28 | at | North Carolina State | 59 | ||||
| Pittsburgh | 25 | at | SMU | 48 | ||||
| Virginia Tech | 31 | at | Syracuse | 38 | OT | |||
| 11/8/2024 | California | at | Wake Forest | |||||
| 11/9/2024 | Syracuse | at | Boston College | |||||
| Miami-Florida | at | Georgia Tech | ||||||
| Duke | at | North Carolina State | ||||||
| Florida State | at | Notre Dame | @ ND | |||||
| Virginia | at | Pittsburgh | ||||||
| Clemson | at | Virginia Tech | ||||||
| 11/16/2024 | Syracuse | at | California | |||||
| Wake Forest | at | North Carolina | ||||||
| Virginia | at | Notre Dame | @ ND | |||||
| Clemson | at | Pittsburgh | ||||||
| Boston College | at | SMU | ||||||
| Louisville | at | Stanford | ||||||
| 11/21/2024 | North Carolina State | at | Georgia Tech | |||||
| 11/23/2024 | North Carolina | at | Boston College | |||||
| Stanford | at | California | ||||||
| The Citadel | at | Clemson | SoCon (1AA) | |||||
| Virginia Tech | at | Duke | ||||||
| Charleston Southern | at | Florida State | BigS (1AA) | |||||
| Pittsburgh | at | Louisville | ||||||
| Wake Forest | at | Miami-Florida | ||||||
| Connecticut | at | Syracuse | Ind | |||||
| SMU | at | Virginia | ||||||
| 11/29/2024 | Georgia Tech | at | Georgia | @ SEC | ||||
| Stanford | at | San Jose State | @ MW | |||||
| 11/30/2024 | Pittsburgh | at | Boston College | |||||
| South Carolina | at | Clemson | SEC | |||||
| Florida | at | Florida State | SEC | |||||
| Louisville | at | Kentucky | @ SEC | |||||
| North Carolina State | at | North Carolina | ||||||
| California | at | SMU | ||||||
| Miami-Florida | at | Syracuse | ||||||
| Virginia | at | Virginia Tech | ||||||
| Duke | at | Wake Forest |