| 8/31/2024 | Penn State | 34 | at | West Virginia (6-6) | 12 | | | at B12 |
| 9/7/2024 | Bowling Green (7-6) | 27 | at | Penn State | 34 | | | MAC |
| 9/21/2024 | Kent State (0-12) | 0 | at | Penn State | 56 | | | MAC |
| 9/28/2024 | Illinois (10-3,6-3) | 7 | at | Penn State | 21 | | | |
| 10/5/2024 | UCLA (5-7,3-6) | 11 | at | Penn State | 27 | | | |
| 10/12/2024 | Penn State | 33 | at | Southern California (7-6,4-5) | 30 | | | |
| 10/26/2024 | Penn State | 28 | at | Wisconsin (5-7,3-6) | 13 | | | |
| 11/2/2024 | Ohio State (14-2,8-2) | 20 | at | Penn State | 13 | | | |
| 11/9/2024 | Washington (6-7,4-5) | 6 | at | Penn State | 35 | | | |
| 11/16/2024 | Penn State | 49 | at | Purdue (1-11,0-9) | 10 | | | |
| 11/23/2024 | Penn State | 26 | at | Minnesota (8-5,5-4) | 25 | | | |
| 11/30/2024 | Maryland (4-8,1-8) | 7 | at | Penn State | 44 | | | |
| 12/7/2024 | Penn State | 27 | vs | Oregon (13-1,10-1) | 45 | | B10 Championship - Indianapolis IN | |
| 12/21/2024 | SMU (11-3) | 10 | at | Penn State | 38 | | FBS Playoff round 1 | ACC |
| 12/31/2024 | Penn State | 31 | vs | Boise State (12-2) | 14 | | FBS Quarterfinal - Fiesta Bowl - Glendale AZ | vs MW |
| 1/9/2025 | Notre Dame (14-2) | 27 | vs | Penn State | 24 | | FBS Semifinal - Orange Bowl - Miami Gardens FL | ND |