| 9/4/2021 | Morrisville (2-8) | 14 | at | Union NY | 48 | E8 | ||
| 9/11/2021 | Union NY | 62 | at | Worcester State (3-7) | 13 | at MSCAC | ||
| 9/18/2021 | Springfield (7-4) | 23 | at | Union NY | 30 | NEWMAC | ||
| 9/25/2021 | Union NY | 30 | at | Utica (6-5) | 9 | at E8 | ||
| 10/2/2021 | Union NY | 30 | at | Buffalo State (0-10) | 17 | at E8 | ||
| 10/9/2021 | St Lawrence (5-5,1-4) | 7 | at | Union NY | 37 | |||
| 10/23/2021 | Union NY | 35 | at | Rochester (3-7,0-5) | 9 | |||
| 10/30/2021 | Hobart (9-2,3-2) | 20 | at | Union NY | 27 | OT | ||
| 11/6/2021 | Union NY | 7 | at | Ithaca (8-2,4-1) | 26 | |||
| 11/13/2021 | Rensselaer (11-2,4-1) | 19 | at | Union NY | 17 |
| vs Union NY | vs Other Opponents | Union NY compared to OOs | |
| Record: | 2-8 | 52-44 | |
| Points Scored: | 15.70 | 23.28 | 7.58 |
| Points Allowed: | 32.30 | 22.13 | 10.17 |
| Margin: | -16.60 | 1.15 | 17.75 |
| Total Points: | 48.00 | 45.41 | 2.59 |