| 9/2/2021 | Lakeland | 28 | at | Illinois College (5-5) | 18 | at MidW | ||
| 9/11/2021 | Lakeland | 54 | at | Anderson (1-9) | 41 | at HCA | ||
| 9/18/2021 | Wisconsin Lutheran (3-7,3-5) | 7 | at | Lakeland | 56 | |||
| 9/25/2021 | St Norbert (5-5,4-4) | 8 | at | Lakeland | 40 | |||
| 10/9/2021 | Lakeland | 40 | at | Ill. Benedictine (8-2,7-1) | 54 | |||
| 10/16/2021 | Lakeland | 63 | at | Concordia IL (3-7,1-7) | 7 | |||
| 10/23/2021 | Concordia WI (6-4,4-4) | 32 | at | Lakeland | 49 | |||
| 10/30/2021 | Lakeland | 45 | at | Eureka (2-8,2-6) | 16 | |||
| 11/6/2021 | Aurora (8-3,8-0) | 38 | at | Lakeland | 20 | |||
| 11/13/2021 | Lakeland | 56 | at | Rockford (2-8,1-7) | 28 |
| vs Lakeland | vs Other Opponents | Lakeland compared to OOs | |
| Record: | 2-8 | 41-50 | |
| Points Scored: | 24.90 | 30.78 | 5.88 |
| Points Allowed: | 45.10 | 34.67 | 10.43 |
| Margin: | -20.20 | -3.89 | 16.31 |
| Total Points: | 70.00 | 65.45 | 4.55 |