| 9/4/2021 | Western New Mexico | 35 | at | Adams State (1-10) | 17 | at RMAC | ||
| 9/11/2021 | Western Colorado (10-2) | 49 | at | Western New Mexico | 14 | RMAC | ||
| 9/18/2021 | Western New Mexico | 14 | at | West Texas A&M (7-4,5-2) | 42 | |||
| 9/25/2021 | Texas-Permian Basin (5-6,3-4) | 27 | at | Western New Mexico | 19 | |||
| 10/2/2021 | Western New Mexico | 3 | at | Angelo State (11-3,5-2) | 62 | |||
| 10/9/2021 | Eastern New Mexico (4-7,1-6) | 50 | at | Western New Mexico | 47 | |||
| 10/16/2021 | Western New Mexico | 0 | at | Texas A&M-Commerce (7-4,5-2) | 58 | |||
| 10/23/2021 | Texas A&M-Kingsville (5-5,3-4) | 28 | at | Western New Mexico | 19 | |||
| 10/30/2021 | Western New Mexico | 10 | at | Midwestern State (7-3,6-1) | 52 | |||
| 11/6/2021 | Central Washington (8-3) | 54 | at | Western New Mexico | 29 | GNWAC |
| vs Western New Mexico | vs Other Opponents | Western New Mexico compared to OOs | |
| Record: | 9-1 | 56-46 | |
| Points Scored: | 43.90 | 30.80 | -13.10 |
| Points Allowed: | 19.00 | 24.12 | -5.12 |
| Margin: | 24.90 | 6.68 | -18.22 |
| Total Points: | 62.90 | 54.92 | 7.98 |