| 9/4/2021 | Brevard | 14 | at | Shorter (3-8) | 38 | at GSC | ||
| 9/11/2021 | Apprentice (1-7) | 34 | at | Brevard | 27 | OT | None (Unk?) | |
| 9/18/2021 | Brevard | 32 | at | North Carolina Wesleyan (4-6,2-4) | 7 | |||
| 9/25/2021 | Huntingdon AL (8-3,6-0) | 21 | at | Brevard | 14 | |||
| 10/2/2021 | Brevard | 27 | at | Greensboro (0-10,0-6) | 7 | |||
| 10/9/2021 | Maryville (4-6,3-3) | 0 | at | Brevard | 31 | |||
| 10/16/2021 | Brevard | 20 | at | LaGrange (2-8,1-5) | 10 | |||
| 10/23/2021 | Southern Virginia (2-8) | 3 | at | Brevard | 7 | ODC | ||
| 10/30/2021 | Brevard | 27 | at | Methodist (7-2,5-1) | 31 | |||
| 11/13/2021 | Averett (5-5) | 3 | at | Brevard | 40 | ODC |
| vs Brevard | vs Other Opponents | Brevard compared to OOs | |
| Record: | 4-6 | 32-57 | |
| Points Scored: | 15.40 | 23.11 | 7.71 |
| Points Allowed: | 23.90 | 29.46 | -5.56 |
| Margin: | -8.50 | -6.35 | 2.15 |
| Total Points: | 39.30 | 52.57 | -13.27 |