| 9/11/2021 | Apprentice | 34 | at | Brevard (6-4) | 27 | OT | at USASC | |
| 9/18/2021 | Apprentice | 7 | at | Emory & Henry (6-4) | 63 | at D2Ind | ||
| 9/25/2021 | Apprentice | 28 | at | Ferrum (6-4) | 30 | at ODC | ||
| 10/2/2021 | Guilford (1-7) | at | Apprentice | Canceled | ODC (D3) | |||
| 10/9/2021 | Apprentice | 13 | at | Washington and Lee (8-3) | 42 | at ODC | ||
| 10/16/2021 | Apprentice | 7 | at | Bridgewater VA (4-6) | 27 | at ODC | ||
| 10/23/2021 | Apprentice | 7 | at | Randolph-Macon (9-1) | 49 | at ODC | ||
| 10/30/2021 | Hampden-Sydney (5-5) | 38 | at | Apprentice | 21 | ODC (D3) | ||
| 11/6/2021 | Apprentice | 16 | at | Shenandoah (7-3) | 35 | at ODC |
| vs Apprentice | vs Other Opponents | Apprentice compared to OOs | |
| Record: | 7-1 | 45-36 | |
| Points Scored: | 38.88 | 27.05 | -11.83 |
| Points Allowed: | 16.63 | 24.16 | -7.53 |
| Margin: | 22.25 | 2.89 | -19.36 |
| Total Points: | 55.51 | 51.21 | 4.30 |