| 9/4/2015 | Michigan State (12-2) | 37 | at | Western Michigan | 24 | B10 | ||
| 9/12/2015 | Western Michigan | 17 | at | Georgia Southern (9-4) | 43 | at SBC | ||
| 9/19/2015 | Murray State (3-8) | 20 | at | Western Michigan | 52 | OVC (1AA) | ||
| 9/26/2015 | Western Michigan | 12 | at | Ohio State (12-1) | 38 | at B10 | ||
| 10/10/2015 | Central Michigan (7-6,6-2) | 39 | at | Western Michigan | 41 | |||
| 10/17/2015 | Western Michigan | 49 | at | Ohio (8-5,5-3) | 14 | |||
| 10/24/2015 | Miami-Ohio (3-9,2-6) | 13 | at | Western Michigan | 35 | |||
| 10/29/2015 | Western Michigan | 58 | at | Eastern Michigan (1-11,0-8) | 28 | |||
| 11/5/2015 | Ball State (3-9,2-6) | 7 | at | Western Michigan | 54 | |||
| 11/11/2015 | Bowling Green (10-4,8-1) | 41 | at | Western Michigan | 27 | |||
| 11/18/2015 | Western Michigan | 19 | at | Northern Illinois (8-6,6-3) | 27 | |||
| 11/27/2015 | Western Michigan | 35 | at | Toledo (10-2,6-2) | 30 | |||
| 12/24/2015 | Middle Tenn State (7-6) | 31 | vs | Western Michigan | 45 | Popeyes Bahamas Bowl | CUSA |
| vs Western Michigan | vs Other Opponents | Western Michigan compared to OOs | |
| Record: | 5-8 | 88-65 | |
| Points Scored: | 28.31 | 30.74 | 2.43 |
| Points Allowed: | 36.00 | 26.59 | 9.41 |
| Margin: | -7.69 | 4.15 | 11.84 |
| Total Points: | 64.31 | 57.33 | 6.98 |