| 9/2/2012 | Stillman (6-5) | 28 | vs | Central State | 27 | Dayton OH | SIAC | |
| 9/8/2012 | Central State | 0 | at | Northern Iowa (5-6) | 59 | at MVC | ||
| 9/15/2012 | Urbana (7-4,5-3) | 22 | at | Central State | 28 | |||
| 9/22/2012 | Central State | 36 | at | St Joseph's (6-5,5-3) | 42 | |||
| 9/29/2012 | Central State | 23 | at | William Jewell (2-9,1-7) | 21 | |||
| 10/6/2012 | Missouri S&T (10-1,7-1) | 27 | at | Central State | 21 | |||
| 10/13/2012 | Central State | 13 | at | Indianapolis (10-3,8-0) | 45 | |||
| 10/27/2012 | Quincy (3-8,3-5) | 16 | at | Central State | 32 | |||
| 11/3/2012 | Central State | 13 | at | McKendree (3-7,3-5) | 34 | |||
| 11/10/2012 | Kentucky Wesleyan (2-9,0-8) | 7 | at | Central State | 51 | |||
| 11/17/2012 | Central State | 6 | at | Kentucky State (2-8) | 17 | at SIAC |
| vs Central State | vs Other Opponents | Central State compared to OOs | |
| Record: | 7-4 | 49-61 | |
| Points Scored: | 28.91 | 25.55 | -3.36 |
| Points Allowed: | 22.73 | 28.58 | -5.85 |
| Margin: | 6.18 | -3.03 | -9.21 |
| Total Points: | 51.64 | 54.13 | -2.49 |