| 8/30/2012 | Shorter | 31 | at | Campbell | 20 | @ Pio (1AA) | ||
| 9/1/2012 | West Alabama | 44 | at | Clark Atlanta | 0 | @ SIAC | ||
| Fort Valley State | 31 | at | Delta State | 23 | vs SIAC | |||
| Valdosta State | 24 | at | Saginaw Valley State | 28 | @ GLIAC | |||
| Point | 3 | at | West Georgia | 55 | vs NAIAInd (NAIA) | |||
| 9/2/2012 | North Alabama | 31 | vs | Miles | 30 | Birmingham AL | @ SIAC | |
| 9/8/2012 | Delta State | 26 | at | Elizabeth City State | 7 | @ CIAA | ||
| Shorter | 14 | at | Newberry | 17 | @ SAC | |||
| Harding | 31 | at | North Alabama | 10 | vs GAC | |||
| West Alabama | 6 | at | Samford | 34 | @ SoCon (1AA) | |||
| Fort Valley State | 14 | at | Valdosta State | 62 | vs SIAC | |||
| Tusculum | 29 | at | West Georgia | 38 | vs SAC | |||
| 9/15/2012 | Valdosta State | 43 | vs | Angelo State | 10 | Arlington TX | @ LSC | |
| Shorter | 28 | at | Chowan | 17 | @ CIAA | |||
| West Georgia | 37 | at | Miles | 44 | @ SIAC | |||
| Kentucky Christian | 0 | at | North Alabama | 39 | vs MSC (NAIA) | |||
| Mississippi College | 3 | at | West Alabama | 41 | vs ASWC (D3) | |||
| 9/22/2012 | North Alabama | 20 | at | Delta State | 12 | |||
| Charleston Southern | 23 | at | Shorter | 20 | vs BigS (1AA) | |||
| West Alabama | 39 | at | Valdosta State | 28 | ||||
| 9/27/2012 | Abilene Christian | 34 | at | Delta State | 28 | vs LSC | ||
| 9/29/2012 | Shorter | 0 | at | North Alabama | 41 | |||
| Edward Waters | 10 | at | Valdosta State | 58 | vs NAIAInd (NAIA) | |||
| West Georgia | 20 | at | West Alabama | 24 | ||||
| 10/4/2012 | Midwestern State | 42 | at | West Alabama | 27 | vs LSC | ||
| 10/6/2012 | Point | 13 | at | Shorter | 35 | vs NAIAInd (NAIA) | ||
| North Alabama | 21 | at | Texas A&M-Kingsville | 16 | @ LSC | |||
| Delta State | 38 | at | Tarleton State | 35 | @ LSC | |||
| Valdosta State | 42 | at | West Georgia | 7 | ||||
| 10/13/2012 | West Georgia | 24 | at | Delta State | 33 | |||
| Valdosta State | 24 | at | North Alabama | 21 | ||||
| Ave Maria | 7 | at | Shorter | 37 | vs NAIAInd (NAIA) | |||
| 10/18/2012 | North Alabama | 23 | at | West Georgia | 38 | |||
| 10/20/2012 | Delta State | 41 | at | Valdosta State | 59 | |||
| Shorter | 7 | at | West Alabama | 49 | ||||
| 10/25/2012 | Valdosta State | 37 | at | Shorter | 6 | |||
| 10/27/2012 | West Alabama | 37 | at | Delta State | 7 | |||
| West Texas A&M | 52 | at | West Georgia | 28 | vs LSC | |||
| 11/1/2012 | Texas A&M-Kingsville | 31 | at | Valdosta State | 38 | vs LSC | ||
| 11/3/2012 | West Alabama | 16 | at | Abilene Christian | 22 | @ LSC | ||
| Delta State | 18 | at | Indianapolis | 33 | @ GLV | |||
| Tarleton State | 38 | at | North Alabama | 28 | vs LSC | |||
| Shorter | 24 | at | West Georgia | 20 | ||||
| 11/8/2012 | North Alabama | 27 | at | West Alabama | 42 | |||
| 11/10/2012 | West Georgia | 17 | at | Midwestern State | 35 | @ LSC | ||
| Delta State | 21 | at | Shorter | 32 | ||||
| 11/17/2012 | Miles | 7 | at | West Alabama | 41 | vs SIAC | ||
| 11/24/2012 | West Alabama | 21 | at | Valdosta State | 49 | D2 Playoffs | ||
| 12/1/2012 | Carson-Newman | 26 | at | Valdosta State | 48 | D2 Quarterfinals | vs SAC | |
| 12/8/2012 | Valdosta State | 35 | at | Minnesota State-Mankato | 19 | D2 Semifinals | @ NSIC | |
| 12/15/2012 | Valdosta State | 35 | vs | Winston-Salem State | 7 | D2 Championship - Florence AL | @ CIAA |