| 9/2/2010 | Massachusetts Maritime 12 @ SUNY-Maritime Privateers 15 | |
| 9/11/2010 | Massachusetts Maritime 6 @ Western New England Golden Bears 30 | † |
| 9/18/2010 | Massachusetts Maritime 38 @ MIT Engineers 17 | † |
| 9/25/2010 | Coast Guard Bears 16 @ Massachusetts Maritime 23 | † |
| 10/2/2010 | Massachusetts Maritime 20 @ Framingham State Rams 48 | † |
| 10/9/2010 | Massachusetts Maritime 21 @ Worcester State Lancers 13 | † |
| 10/16/2010 | Fitchburg State Falcons 7 @ Massachusetts Maritime 34 | † |
| 10/23/2010 | Massachusetts Maritime 27 @ Maine Maritime Mariners 28 | † |
| 10/30/2010 | Westfield State Owls 28 @ Massachusetts Maritime 14 | † |
| 11/6/2010 | Bridgewater State MA Bears 7 @ Massachusetts Maritime 23 | † |