| 9/4/2010 | Winston-Salem St | @ | NC A&T | MEAC | |||||
| 9/11/2010 | NC A&T | @ | Norfolk St | MEAC | |||||
| 9/18/2010 | NC A&T | @ | Hampton | MEAC | |||||
| 9/25/2010 | NC A&T | @ | North Carolina Central | ||||||
| 10/2/2010 | NC A&T | vs | Tennessee St | ||||||
| 10/9/2010 | Morgan St | @ | NC A&T | MEAC | |||||
| 10/16/2010 | NC A&T | @ | Delaware St | MEAC | |||||
| 10/23/2010 | Howard | @ | NC A&T | MEAC | |||||
| 10/30/2010 | NC A&T | @ | Bethune-Cookman | MEAC | |||||
| 11/6/2010 | Florida A&M | @ | NC A&T | MEAC | |||||
| 11/20/2010 | S Carolina St | @ | NC A&T | MEAC |