| 9/5/2009 | Rose-Hulman 61 @ Earlham 24 | |
| 9/12/2009 | North Park 17 @ Rose-Hulman 48 | |
| 9/19/2009 | Rose-Hulman 18 @ Greenville 19 | |
| 9/26/2009 | Mt St Joseph 45 @ Rose-Hulman 38 | † |
| 10/3/2009 | Rose-Hulman 17 @ Manchester 20 | † |
| 10/10/2009 | Hanover 38 @ Rose-Hulman 41 | † |
| 10/17/2009 | Defiance 28 @ Rose-Hulman 21 | † |
| 10/24/2009 | Rose-Hulman 50 @ Bluffton 14 | † |
| 10/31/2009 | Franklin 21 @ Rose-Hulman 34 | † |
| 11/7/2009 | Rose-Hulman 37 @ Anderson 6 | † |