| 9/5/2009 | Mt St Joseph 27 @ Wilmington 18 | |
| 9/12/2009 | Lakeland 19 @ Mt St Joseph 42 | |
| 9/26/2009 | Mt St Joseph 45 @ Rose-Hulman 38 | † |
| 10/3/2009 | Bluffton 18 @ Mt St Joseph 38 | † |
| 10/10/2009 | Mt St Joseph 61 @ Anderson 28 | † |
| 10/17/2009 | Hanover 13 @ Mt St Joseph 28 | † |
| 10/24/2009 | Mt St Joseph 26 @ Franklin 16 | † |
| 10/31/2009 | Mt St Joseph 31 @ Manchester 7 | † |
| 11/7/2009 | Defiance 16 @ Mt St Joseph 24 | † |
| 11/14/2009 | Thomas More 42 @ Mt St Joseph 17 | |
| 11/21/2009 | Mt St Joseph 14 @ Wittenberg 42 (D3) |