| 9/7/2009 | Cincinnati 45 @ Rutgers 17 | † |
| 9/12/2009 | SE Missouri St 3 @ Cincinnati 70 | |
| 9/19/2009 | Cincinnati 28 @ Oregon St 18 | |
| 9/26/2009 | Fresno St 20 @ Cincinnati 28 | |
| 10/3/2009 | Cincinnati 37 @ Miami-Ohio 13 | |
| 10/15/2009 | Cincinnati 34 @ South Florida 17 | † |
| 10/24/2009 | Louisville 10 @ Cincinnati 41 | † |
| 10/31/2009 | Cincinnati 28 @ Syracuse 7 | † |
| 11/7/2009 | Connecticut 45 @ Cincinnati 47 | † |
| 11/13/2009 | West Virginia 21 @ Cincinnati 24 | † |
| 11/27/2009 | Illinois 36 @ Cincinnati 49 | |
| 12/5/2009 | Cincinnati 45 @ Pittsburgh 44 | † |
| 1/1/2010 | Cincinnati 24 vs Florida 51 (Sugar Bowl) |