| 9/5/2009 | Nevada 0 @ Notre Dame 35 |
| 9/12/2009 | Notre Dame 34 @ Michigan 38 |
| 9/19/2009 | Michigan St 30 @ Notre Dame 33 |
| 9/26/2009 | Notre Dame 24 @ Purdue 21 |
| 10/3/2009 | Washington 30 @ Notre Dame 37 1OT |
| 10/17/2009 | Southern California 34 @ Notre Dame 27 |
| 10/24/2009 | Boston College 16 @ Notre Dame 20 |
| 10/31/2009 | Washington St 14 vs Notre Dame 40 (San Antonio TX) |
| 11/7/2009 | Navy 23 @ Notre Dame 21 |
| 11/14/2009 | Notre Dame 22 @ Pittsburgh 27 |
| 11/21/2009 | Connecticut 33 @ Notre Dame 30 2OT |
| 11/28/2009 | Notre Dame 38 @ Stanford 45 |