| 9/3/2020 | South Alabama | 32 | at | Southern Miss | 21 | @ CUSA | ||
| 9/5/2020 | Arkansas State | 24 | at | Memphis | 37 | @ AAC | ||
| SMU | 31 | at | Texas State | 24 | AAC | |||
| 9/12/2020 | UNC-Charlotte | 20 | at | Appalachian State | 35 | CUSA | ||
| UL Monroe | 7 | at | Army | 37 | @ Ind | |||
| Campbell | 26 | at | Georgia Southern | 27 | BigS (1AA) | |||
| UL Lafayette | 31 | at | Iowa State | 14 | @ B12 | |||
| Coastal Carolina | 38 | at | Kansas | 23 | @ B12 | |||
| Arkansas State | 35 | at | Kansas State | 31 | @ B12 | |||
| Tulane | 27 | at | South Alabama | 24 | AAC | |||
| Texas-San Antonio | 51 | at | Texas State | 48 | CUSA | |||
| 9/18/2020 | Campbell | 21 | at | Coastal Carolina | 43 | BigS (1AA) | ||
| 9/19/2020 | UL Lafayette | 34 | at | Georgia State | 31 | |||
| Appalachian State | 7 | at | Marshall | 17 | @ CUSA | |||
| Troy | 47 | at | Middle Tenn State | 14 | @ CUSA | |||
| Texas State | 38 | at | UL Monroe | 17 | ||||
| 9/24/2020 | UAB | 42 | at | South Alabama | 10 | CUSA | ||
| 9/26/2020 | Campbell | 21 | at | Appalachian State | 52 | BigS (1AA) | ||
| Texas State | 21 | at | Boston College | 24 | @ ACC | |||
| Troy | 7 | at | BYU | 48 | @ Ind | |||
| Georgia Southern | 18 | at | UL Lafayette | 20 | ||||
| UTEP | 31 | at | UL Monroe | 6 | CUSA | |||
| 10/3/2020 | Arkansas State | 23 | at | Coastal Carolina | 52 | |||
| East Carolina | 29 | at | Georgia State | 49 | AAC | |||
| Georgia Southern | 35 | at | UL Monroe | 30 | ||||
| 10/10/2020 | Central Arkansas | 27 | at | Arkansas State | 50 | SLC (1AA) | ||
| UL Monroe | 7 | at | Liberty | 40 | @ Ind | |||
| Texas State | 17 | at | Troy | 37 | ||||
| 10/14/2020 | Coastal Carolina | 30 | at | UL Lafayette | 27 | |||
| 10/15/2020 | Georgia State | 52 | at | Arkansas State | 59 | |||
| 10/17/2020 | Massachusetts | at | Georgia Southern | Ind | ||||
| Texas State | at | South Alabama | ||||||
| Eastern Kentucky | at | Troy | OVC (1AA) | |||||
| 10/22/2020 | Arkansas State | at | Appalachian State | |||||
| 10/23/2020 | UL Lafayette | at | UAB | @ CUSA | ||||
| 10/24/2020 | Texas State | at | BYU | @ Ind | ||||
| Georgia Southern | at | Coastal Carolina | ||||||
| UL Monroe | at | South Alabama | ||||||
| Georgia State | at | Troy | ||||||
| 10/29/2020 | South Alabama | at | Georgia Southern | |||||
| Coastal Carolina | at | Georgia State | ||||||
| 10/31/2020 | Troy | at | Arkansas State | |||||
| UL Lafayette | at | Texas State | ||||||
| Appalachian State | at | UL Monroe | ||||||
| 11/5/2020 | Arkansas State | at | UL Lafayette | |||||
| 11/7/2020 | South Alabama | at | Coastal Carolina | |||||
| Troy | at | Georgia Southern | ||||||
| UL Monroe | at | Georgia State | ||||||
| Appalachian State | at | Texas State | ||||||
| 11/14/2020 | Georgia State | at | Appalachian State | |||||
| UL Monroe | at | Arkansas State | ||||||
| Texas State | at | Georgia Southern | ||||||
| South Alabama | at | UL Lafayette | ||||||
| Coastal Carolina | at | Troy | ||||||
| 11/21/2020 | Georgia Southern | at | Army | @ Ind | ||||
| Appalachian State | at | Coastal Carolina | ||||||
| Central Arkansas | at | UL Lafayette | SLC (1AA) | |||||
| UL Monroe | at | Louisiana Tech | Shreveport, LA | @ CUSA | ||||
| Georgia State | at | South Alabama | ||||||
| Arkansas State | at | Texas State | ||||||
| Middle Tenn State | at | Troy | CUSA | |||||
| 11/28/2020 | Troy | at | Appalachian State | |||||
| South Alabama | at | Arkansas State | ||||||
| Georgia Southern | at | Georgia State | ||||||
| Coastal Carolina | at | Texas State | ||||||
| UL Lafayette | at | UL Monroe | ||||||
| 12/5/2020 | Liberty | at | Coastal Carolina | Ind | ||||
| Florida Atlantic | at | Georgia Southern | CUSA | |||||
| UL Monroe | at | Troy | ||||||
| 12/12/2020 | Appalachian State | at | Georgia Southern | |||||
| Troy | at | South Alabama |