| 8/31/2024 | Illinois State (10-4) | 0 | at | Iowa | 40 | MVC (1AA) | ||
| 9/7/2024 | Iowa State (10-3) | 20 | at | Iowa | 19 | B12 | ||
| 9/14/2024 | Troy (4-8) | 21 | at | Iowa | 38 | SBC | ||
| 9/21/2024 | Iowa | 31 | at | Minnesota (7-5,5-4) | 14 | |||
| 10/5/2024 | Iowa | 7 | at | Ohio State (11-2,7-2) | 35 | |||
| 10/12/2024 | Washington (6-6,4-5) | 16 | at | Iowa | 40 | |||
| 10/19/2024 | Iowa | 20 | at | Michigan State (5-7,3-6) | 32 | |||
| 10/26/2024 | Northwestern (4-8,2-7) | 14 | at | Iowa | 40 | |||
| 11/2/2024 | Wisconsin (5-7,3-6) | 10 | at | Iowa | 42 | |||
| 11/8/2024 | Iowa | 17 | at | UCLA (5-7,3-6) | 20 | |||
| 11/23/2024 | Iowa | 29 | at | Maryland (4-8,1-8) | 13 | |||
| 11/29/2024 | Nebraska (6-6,3-6) | 10 | at | Iowa | 13 | |||
| 12/30/2024 | Iowa | vs | Missouri (9-3) | Music City Bowl - Nashville TN | vs SEC |
| vs Iowa | vs Other Opponents | Iowa compared to OOs | |
| Record: | 4-8 | 82-66 | |
| Points Scored: | 17.08 | 25.57 | 8.49 |
| Points Allowed: | 28.00 | 22.43 | 5.57 |
| Margin: | -10.92 | 3.14 | 14.06 |
| Total Points: | 45.08 | 48.00 | -2.92 |