| 9/3/2022 | Avila | 41 | at | Tabor (6-5,5-5) | 7 | | | |
| 9/10/2022 | Ottawa (2-8,2-8) | 9 | at | Avila | 39 | | | |
| 9/17/2022 | Avila | 21 | at | Bethany KS (0-10,0-10) | 0 | | | |
| 9/24/2022 | Avila | 21 | at | Southwestern (9-2,9-1) | 24 | | | |
| 10/1/2022 | Sterling (2-8,2-8) | 14 | at | Avila | 44 | | | |
| 10/8/2022 | Avila | 18 | at | Kansas Wesleyan (8-3,7-3) | 14 | | | |
| 10/15/2022 | Bethel KS (9-1,9-1) | 14 | at | Avila | 28 | | | |
| 10/22/2022 | St Mary KS (4-7,4-6) | 21 | at | Avila | 34 | | | |
| 10/29/2022 | Avila | 36 | at | Arkansas Baptist (1-7) | 6 | | | at None |
| 11/5/2022 | Avila | 43 | at | McPherson (5-5,5-5) | 23 | | | |
| 11/12/2022 | Friends (4-7,3-7) | 26 | at | Avila | 42 | | | |
| 11/19/2022 | Avila | 7 | at | Indiana Wesleyan (10-2) | 14 | | NAIA Championship Round 1 | at MSFA |