| 9/3/2022 | McPherson | 13 | at | Bethel KS (9-1,9-1) | 14 | |||
| 9/10/2022 | Tabor (6-5,5-5) | 17 | at | McPherson | 16 | |||
| 9/17/2022 | McPherson | 27 | at | Ottawa (2-8,2-8) | 18 | |||
| 10/1/2022 | McPherson | 22 | at | Southwestern (9-2,9-1) | 23 | |||
| 10/8/2022 | Friends (4-7,3-7) | 22 | at | McPherson | 31 | |||
| 10/15/2022 | Kansas Wesleyan (8-3,7-3) | 14 | at | McPherson | 12 | |||
| 10/22/2022 | McPherson | 53 | at | Bethany KS (0-10,0-10) | 6 | |||
| 10/29/2022 | St Mary KS (4-7,4-6) | 10 | at | McPherson | 21 | |||
| 11/5/2022 | Avila (10-2,9-1) | 43 | at | McPherson | 23 | |||
| 11/12/2022 | McPherson | 47 | at | Sterling (2-8,2-8) | 10 |
| vs McPherson | vs Other Opponents | McPherson compared to OOs | |
| Record: | 5-5 | 49-48 | |
| Points Scored: | 17.70 | 24.88 | 7.18 |
| Points Allowed: | 26.50 | 24.68 | 1.82 |
| Margin: | -8.80 | 0.20 | 9.00 |
| Total Points: | 44.20 | 49.56 | -5.36 |