| 9/2/2022 | Worcester Polytechnic (4-6) | 58 | at | Worcester State | 21 | NEWMAC | ||
| 9/10/2022 | Worcester State | 7 | at | Union NY (6-4) | 76 | at LL | ||
| 9/17/2022 | Worcester State | 56 | at | Fitchburg State (1-9,0-8) | 10 | |||
| 9/24/2022 | UMass Dartmouth (9-2,8-0) | 41 | at | Worcester State | 20 | |||
| 10/8/2022 | Worcester State | 0 | at | Bridgewater State MA (7-4,6-2) | 45 | |||
| 10/15/2022 | Massachusetts Maritime (3-7,3-5) | 25 | at | Worcester State | 17 | |||
| 10/22/2022 | Plymouth State (9-2,6-2) | 56 | at | Worcester State | 21 | |||
| 10/29/2022 | Worcester State | 35 | at | Western Connecticut (7-3,6-2) | 38 | |||
| 11/5/2022 | Westfield State (2-8,2-6) | 28 | at | Worcester State | 18 | |||
| 11/11/2022 | Worcester State | 16 | at | Framingham State (5-5,4-4) | 21 |
| vs Worcester State | vs Other Opponents | Worcester State compared to OOs | |
| Record: | 9-1 | 44-49 | |
| Points Scored: | 39.80 | 23.16 | -16.64 |
| Points Allowed: | 21.10 | 24.76 | -3.66 |
| Margin: | 18.70 | -1.60 | -20.30 |
| Total Points: | 60.90 | 47.92 | 12.98 |