| 8/27/2022 | Bluefield (8-3,8-2) | 42 | at | Thomas More | 35 | |||
| 9/3/2022 | Thomas More | 31 | at | Kentucky Christian (3-8,3-7) | 28 | |||
| 9/10/2022 | Thomas More | 14 | at | Duquesne (4-7) | 34 | at NE | ||
| 9/17/2022 | Thomas More | 44 | at | Campbellsville (2-8,2-8) | 36 | |||
| 10/1/2022 | Lindsey Wilson (10-2,10-1) | 12 | at | Thomas More | 3 | |||
| 10/8/2022 | Thomas More | 24 | at | Faulkner (4-7,4-6) | 7 | |||
| 10/15/2022 | Cumberland TN (3-7,2-7) | 16 | at | Thomas More | 24 | |||
| 10/22/2022 | Thomas More | 7 | at | Bethel TN (11-1,10-0) | 57 | |||
| 10/29/2022 | Pikeville (6-4,6-4) | 28 | at | Thomas More | 24 | |||
| 11/5/2022 | Thomas More | 0 | at | Georgetown KY (7-3,7-3) | 35 | |||
| 11/12/2022 | Cumberlands KY (5-5,5-5) | 10 | at | Thomas More | 43 |
| vs Thomas More | vs Other Opponents | Thomas More compared to OOs | |
| Record: | 6-5 | 57-50 | |
| Points Scored: | 27.73 | 28.62 | 0.89 |
| Points Allowed: | 22.64 | 25.74 | -3.10 |
| Margin: | 5.09 | 2.88 | -2.21 |
| Total Points: | 50.37 | 54.36 | -3.99 |