| 9/3/2022 | Susquehanna | 45 | at | Lycoming (4-6) | 16 | at MidAC | ||
| 9/10/2022 | Franklin & Marshall (6-4,5-4) | 36 | at | Susquehanna | 39 | |||
| 9/17/2022 | Moravian (3-7,3-6) | 3 | at | Susquehanna | 37 | |||
| 9/24/2022 | Susquehanna | 45 | at | Dickinson (3-7,3-6) | 0 | |||
| 10/1/2022 | Ursinus (9-2,7-2) | 12 | at | Susquehanna | 17 | |||
| 10/15/2022 | Susquehanna | 41 | at | Gettysburg (1-9,1-8) | 7 | |||
| 10/22/2022 | Susquehanna | 58 | at | McDaniel (3-7,3-6) | 0 | |||
| 10/29/2022 | Johns Hopkins (10-1,8-1) | 24 | at | Susquehanna | 26 | |||
| 11/5/2022 | Susquehanna | 28 | at | Muhlenberg (7-4,6-3) | 24 | |||
| 11/12/2022 | Juniata (0-10,0-9) | 15 | at | Susquehanna | 66 | |||
| 11/19/2022 | Utica (10-2) | 17 | at | Susquehanna | 10 | D3 Championship Round 1 | E8 |
| vs Susquehanna | vs Other Opponents | Susquehanna compared to OOs | |
| Record: | 1-10 | 55-49 | |
| Points Scored: | 14.00 | 26.90 | 12.90 |
| Points Allowed: | 37.45 | 25.81 | 11.64 |
| Margin: | -23.45 | 1.09 | 24.54 |
| Total Points: | 51.45 | 52.71 | -1.26 |