| 9/2/2022 | MIT | 35 | at | Curry (3-7) | 20 | at CCF | ||
| 9/10/2022 | Salve Regina (6-4) | 13 | at | MIT | 10 | CCF | ||
| 9/24/2022 | Dean (1-9) | 6 | at | MIT | 35 | ECFC | ||
| 10/1/2022 | Catholic (6-5,5-1) | 42 | at | MIT | 7 | |||
| 10/15/2022 | Merchant Marine (6-3,4-2) | 17 | at | MIT | 0 | |||
| 10/22/2022 | MIT | 11 | at | Norwich (3-7,2-4) | 21 | |||
| 10/29/2022 | Coast Guard (3-7,1-5) | 31 | at | MIT | 24 | |||
| 11/5/2022 | MIT | 14 | at | Springfield (9-3,6-0) | 16 | |||
| 11/12/2022 | MIT | 21 | at | Worcester Polytechnic (4-6,2-4) | 14 |
| vs MIT | vs Other Opponents | MIT compared to OOs | |
| Record: | 6-3 | 35-48 | |
| Points Scored: | 20.00 | 24.53 | 4.53 |
| Points Allowed: | 17.44 | 27.00 | -9.56 |
| Margin: | 2.56 | -2.47 | -5.03 |
| Total Points: | 37.44 | 51.53 | -14.09 |