| 9/3/2022 | Houston Christian (2-9) | 46 | at | Northern Colorado | 34 | SLC | ||
| 9/10/2022 | Northern Colorado | 10 | at | Wyoming (7-6) | 33 | at MW | ||
| 9/17/2022 | Northern Colorado | 21 | at | Lamar (1-10) | 14 | at SLC | ||
| 9/24/2022 | Idaho State (1-10,1-7) | 14 | at | Northern Colorado | 35 | |||
| 10/1/2022 | Northern Colorado | 35 | at | Idaho (7-5,6-2) | 55 | |||
| 10/8/2022 | Northern Colorado | 7 | at | Sacramento State (12-1,8-0) | 55 | |||
| 10/15/2022 | Montana State (12-2,9-0) | 37 | at | Northern Colorado | 14 | |||
| 10/22/2022 | UC Davis (6-5,5-3) | 58 | at | Northern Colorado | 10 | |||
| 11/5/2022 | Northern Colorado | 21 | at | Portland State (4-7,3-5) | 35 | |||
| 11/12/2022 | Northern Arizona (3-8,2-6) | 20 | at | Northern Colorado | 21 | |||
| 11/19/2022 | Northern Colorado | 21 | at | Eastern Washington (3-8,2-6) | 45 |
| vs Northern Colorado | vs Other Opponents | Northern Colorado compared to OOs | |
| Record: | 8-3 | 50-68 | |
| Points Scored: | 37.45 | 27.36 | -10.09 |
| Points Allowed: | 20.82 | 31.81 | -10.99 |
| Margin: | 16.63 | -4.45 | -21.08 |
| Total Points: | 58.27 | 59.17 | -0.90 |