| 9/4/2021 | Wisconsin-Oshkosh | 28 | at | Huntingdon AL (8-3) | 24 | at USASC | ||
| 9/11/2021 | Wisconsin-Oshkosh | 28 | at | Northern Michigan (4-7) | 10 | at GLIAC | ||
| 10/2/2021 | Wisconsin-Oshkosh | 35 | at | Wisconsin-Platteville (4-6,3-4) | 32 | |||
| 10/9/2021 | Wisconsin-Oshkosh | 21 | at | Wisconsin-La Crosse (9-3,6-1) | 30 | |||
| 10/16/2021 | Wisconsin-Whitewater (13-1,7-0) | 32 | at | Wisconsin-Oshkosh | 13 | |||
| 10/23/2021 | Wisconsin-Eau Claire (3-7,1-6) | 31 | at | Wisconsin-Oshkosh | 54 | |||
| 10/30/2021 | Wisconsin-Oshkosh | 43 | at | Wisconsin-Stout (5-5,3-5) | 36 | |||
| 11/6/2021 | Wisconsin-Stevens Point (2-8,0-8) | 17 | at | Wisconsin-Oshkosh | 49 | |||
| 11/13/2021 | Wisconsin-River Falls (9-2,5-2) | 28 | at | Wisconsin-Oshkosh | 21 |
| vs Wisconsin-Oshkosh | vs Other Opponents | Wisconsin-Oshkosh compared to OOs | |
| Record: | 3-6 | 54-36 | |
| Points Scored: | 26.67 | 32.73 | 6.06 |
| Points Allowed: | 32.44 | 25.61 | 6.83 |
| Margin: | -5.77 | 7.12 | 12.89 |
| Total Points: | 59.11 | 58.34 | 0.77 |