| 9/26/2020 | Mississippi State | 44 | at | LSU (5-5,5-5) | 34 | |||
| 10/3/2020 | Arkansas (3-7,3-7) | 21 | at | Mississippi State | 14 | |||
| 10/10/2020 | Mississippi State | 2 | at | Kentucky (5-6,4-6) | 24 | |||
| 10/17/2020 | Texas A&M (9-1,8-1) | 28 | at | Mississippi State | 14 | |||
| 10/31/2020 | Mississippi State | 0 | at | Alabama (13-0,11-0) | 41 | |||
| 11/7/2020 | Vanderbilt (0-9,0-9) | 17 | at | Mississippi State | 24 | |||
| 11/14/2020 | Auburn (6-5,6-4) | at | Mississippi State | PPD | ||||
| 11/21/2020 | Mississippi State | 24 | at | Georgia (8-2,7-2) | 31 | |||
| 11/28/2020 | Mississippi State | 24 | at | Mississippi (5-5,4-5) | 31 | |||
| 12/12/2020 | Auburn (6-5,6-4) | 24 | at | Mississippi State | 10 | |||
| 12/19/2020 | Missouri (5-5,5-5) | 32 | at | Mississippi State | 51 | |||
| 12/31/2020 | Tulsa (6-3) | 26 | vs | Mississippi State | 28 | Armed Forces Bowl | AAC |
| vs Mississippi State | vs Other Opponents | Mississippi State compared to OOs | |
| Record: | 7-4 | 63-49 | |
| Points Scored: | 28.09 | 30.13 | 2.04 |
| Points Allowed: | 21.36 | 28.54 | -7.18 |
| Margin: | 6.73 | 1.59 | -5.14 |
| Total Points: | 49.45 | 58.67 | -9.22 |