| 9/26/2020 | Tennessee (3-7,3-7) | 31 | at | South Carolina | 27 | |||
| 10/3/2020 | South Carolina | 24 | at | Florida (8-4,8-3) | 38 | |||
| 10/10/2020 | South Carolina | 41 | at | Vanderbilt (0-9,0-9) | 7 | |||
| 10/17/2020 | Auburn (6-5,6-4) | 22 | at | South Carolina | 30 | |||
| 10/24/2020 | South Carolina | 24 | at | LSU (5-5,5-5) | 52 | |||
| 11/7/2020 | Texas A&M (9-1,8-1) | 48 | at | South Carolina | 3 | |||
| 11/14/2020 | South Carolina | 42 | at | Mississippi (5-5,4-5) | 59 | |||
| 11/21/2020 | Missouri (5-5,5-5) | 17 | at | South Carolina | 10 | |||
| 11/28/2020 | Georgia (8-2,7-2) | 45 | at | South Carolina | 16 | |||
| 12/5/2020 | South Carolina | 18 | at | Kentucky (5-6,4-6) | 41 | |||
| 12/26/2020 | South Carolina | vs | UAB (6-3) | CCD Gasparilla Bowl | vs CUSA |
| vs South Carolina | vs Other Opponents | South Carolina compared to OOs | |
| Record: | 8-2 | 52-50 | |
| Points Scored: | 36.00 | 28.10 | -7.90 |
| Points Allowed: | 23.50 | 29.35 | -5.85 |
| Margin: | 12.50 | -1.25 | -13.75 |
| Total Points: | 59.50 | 57.45 | 2.05 |