| 8/31/2019 | Mississippi State | 38 | vs | UL Lafayette (11-3) | 28 | New Orleans LA | vs SBC | |
| 9/7/2019 | Southern Miss (7-6) | 15 | at | Mississippi State | 38 | CUSA | ||
| 9/14/2019 | Kansas State (8-5) | 31 | at | Mississippi State | 24 | B12 | ||
| 9/21/2019 | Kentucky (8-5,3-5) | 13 | at | Mississippi State | 28 | |||
| 9/28/2019 | Mississippi State | 23 | at | Auburn (9-4,5-3) | 56 | |||
| 10/12/2019 | Mississippi State | 10 | at | Tennessee (8-5,5-3) | 20 | |||
| 10/19/2019 | LSU (15-0,9-0) | 36 | at | Mississippi State | 13 | |||
| 10/26/2019 | Mississippi State | 30 | at | Texas A&M (8-5,4-4) | 49 | |||
| 11/2/2019 | Mississippi State | 54 | at | Arkansas (2-10,0-8) | 24 | |||
| 11/16/2019 | Alabama (11-2,6-2) | 38 | at | Mississippi State | 7 | |||
| 11/23/2019 | Abilene Christian (5-7) | 7 | at | Mississippi State | 45 | SLC (1AA) | ||
| 11/28/2019 | Mississippi (4-8,2-6) | 20 | at | Mississippi State | 21 | |||
| 12/30/2019 | Mississippi State | 28 | vs | Louisville (8-5) | 38 | Music City Bowl - Nashville TN | vs ACC |
| vs Mississippi State | vs Other Opponents | Mississippi State compared to OOs | |
| Record: | 7-6 | 97-59 | |
| Points Scored: | 28.85 | 32.38 | 3.53 |
| Points Allowed: | 27.62 | 23.87 | 3.75 |
| Margin: | 1.23 | 8.51 | 7.28 |
| Total Points: | 56.47 | 56.25 | 0.22 |