| 8/31/2019 | Eastern Michigan (6-7) | 30 | at | Coastal Carolina | 23 | MAC | ||
| 9/7/2019 | Coastal Carolina | 12 | at | Kansas (3-9) | 7 | at B12 | ||
| 9/14/2019 | Norfolk State (5-7) | 7 | at | Coastal Carolina | 46 | MEAC (1AA) | ||
| 9/21/2019 | Coastal Carolina | 62 | at | Massachusetts (1-11) | 28 | at Ind | ||
| 9/28/2019 | Coastal Carolina | 37 | at | Appalachian State (13-1,8-1) | 56 | |||
| 10/12/2019 | Georgia State (7-6,4-4) | 31 | at | Coastal Carolina | 21 | |||
| 10/19/2019 | Coastal Carolina | 27 | at | Georgia Southern (7-6,5-3) | 30 | 3OT | ||
| 11/2/2019 | Troy (5-7,3-5) | 35 | at | Coastal Carolina | 36 | |||
| 11/7/2019 | UL Lafayette (11-3,7-2) | 48 | at | Coastal Carolina | 7 | |||
| 11/16/2019 | Coastal Carolina | 27 | at | Arkansas State (8-5,5-3) | 28 | |||
| 11/23/2019 | Coastal Carolina | 42 | at | UL Monroe (5-7,4-4) | 45 | |||
| 11/30/2019 | Texas State (3-9,2-6) | 21 | at | Coastal Carolina | 24 |
| vs Coastal Carolina | vs Other Opponents | Coastal Carolina compared to OOs | |
| Record: | 7-5 | 67-73 | |
| Points Scored: | 30.50 | 29.78 | -0.72 |
| Points Allowed: | 30.33 | 32.55 | -2.22 |
| Margin: | 0.17 | -2.77 | -2.94 |
| Total Points: | 60.83 | 62.33 | -1.50 |