| 8/30/2018 | California PA (7-4) | 23 | at | Ohio Dominican | 28 | PSAC | ||
| 9/8/2018 | Ashland (6-4) | 17 | at | Ohio Dominican | 24 | GLIAC | ||
| 9/15/2018 | Hillsdale (10-3,7-0) | 34 | at | Ohio Dominican | 18 | |||
| 9/22/2018 | Ohio Dominican | 34 | at | Findlay (8-3,5-2) | 21 | |||
| 9/29/2018 | Alderson-Broaddus (4-7,3-4) | 27 | at | Ohio Dominican | 66 | |||
| 10/6/2018 | Ohio Dominican | 20 | at | Walsh (4-6,4-3) | 10 | |||
| 10/13/2018 | Malone (2-8,1-6) | 17 | at | Ohio Dominican | 57 | |||
| 10/20/2018 | Ohio Dominican | 23 | at | Tiffin (9-2) | 24 | at GLIAC | ||
| 10/27/2018 | Ohio Dominican | 48 | at | East Stroudsburg (2-9) | 35 | at PSAC | ||
| 11/3/2018 | Kentucky Wesleyan (3-7,2-5) | 7 | at | Ohio Dominican | 65 | |||
| 11/10/2018 | Ohio Dominican | 62 | at | Lake Erie (0-11,0-7) | 6 |
| vs Ohio Dominican | vs Other Opponents | Ohio Dominican compared to OOs | |
| Record: | 2-9 | 53-55 | |
| Points Scored: | 20.09 | 28.64 | 8.55 |
| Points Allowed: | 40.45 | 29.66 | 10.79 |
| Margin: | -20.36 | -1.02 | 19.34 |
| Total Points: | 60.54 | 58.30 | 2.24 |