| 9/1/2018 | Edinboro (6-5) | 69 | at | Lake Erie | 0 | PSAC | ||
| 9/8/2018 | Lake Erie | 12 | at | Malone (2-8,1-6) | 42 | |||
| 9/13/2018 | Lake Erie | 19 | at | Urbana (5-6) | 27 | at MtnE | ||
| 9/22/2018 | Lake Erie | 7 | at | Hillsdale (10-3,7-0) | 41 | |||
| 9/29/2018 | Findlay (8-3,5-2) | 70 | at | Lake Erie | 7 | |||
| 10/6/2018 | Lake Erie | 27 | at | Alderson-Broaddus (4-7,3-4) | 55 | |||
| 10/13/2018 | Walsh (4-6,4-3) | 29 | at | Lake Erie | 0 | |||
| 10/20/2018 | Lake Erie | 6 | at | Kentucky Wesleyan (3-7,2-5) | 46 | |||
| 10/27/2018 | Tiffin (9-2) | 40 | at | Lake Erie | 28 | GLIAC | ||
| 11/3/2018 | Lake Erie | 0 | at | Thomas More (7-3) | 44 | at D3Ind | ||
| 11/10/2018 | Ohio Dominican (9-2,6-1) | 62 | at | Lake Erie | 6 |
| vs Lake Erie | vs Other Opponents | Lake Erie compared to OOs | |
| Record: | 11-0 | 56-52 | |
| Points Scored: | 47.73 | 29.23 | -18.50 |
| Points Allowed: | 10.18 | 29.40 | -19.22 |
| Margin: | 37.55 | -0.17 | -37.72 |
| Total Points: | 57.91 | 58.63 | -0.72 |