| 8/25/2018 | Duquesne (9-4) | 15 | at | Massachusetts | 63 | NE (1AA) | ||
| 9/1/2018 | Massachusetts | 21 | at | Boston College (7-5) | 55 | at ACC | ||
| 9/8/2018 | Massachusetts | 13 | at | Georgia Southern (10-3) | 34 | at SBC | ||
| 9/15/2018 | Massachusetts | 24 | at | Florida Intl (9-4) | 63 | at CUSA | ||
| 9/22/2018 | UNC-Charlotte (5-7) | 31 | at | Massachusetts | 49 | CUSA | ||
| 9/29/2018 | Massachusetts | 42 | at | Ohio (9-4) | 58 | at MAC | ||
| 10/6/2018 | South Florida (7-6) | 58 | at | Massachusetts | 42 | AAC | ||
| 10/20/2018 | Coastal Carolina (5-7) | 24 | at | Massachusetts | 13 | SBC | ||
| 10/27/2018 | Massachusetts | 22 | at | Connecticut (1-11) | 17 | at AAC | ||
| 11/3/2018 | Liberty (6-6,1-3) | 59 | at | Massachusetts | 62 | 3OT | ||
| 11/10/2018 | BYU (7-6,2-0) | 35 | vs | Massachusetts | 16 | Foxboro MA | ||
| 11/17/2018 | Massachusetts | 27 | at | Georgia (11-3) | 66 | at SEC |
| vs Massachusetts | vs Other Opponents | Massachusetts compared to OOs | |
| Record: | 8-4 | 78-62 | |
| Points Scored: | 42.92 | 29.39 | -13.53 |
| Points Allowed: | 32.83 | 28.09 | 4.74 |
| Margin: | 10.09 | 1.30 | -8.79 |
| Total Points: | 75.75 | 57.48 | 18.27 |