| 8/30/2017 | Northwestern Oklahoma State | 28 | at | Ouachita (9-3,9-2) | 31 | | | |
| 9/9/2017 | Arkansas-Monticello (5-6,5-6) | 37 | at | Northwestern Oklahoma State | 35 | | | |
| 9/16/2017 | Northwestern Oklahoma State | 36 | at | Henderson State (6-5,6-5) | 30 | | | |
| 9/23/2017 | Southern Arkansas (7-4,7-4) | 16 | at | Northwestern Oklahoma State | 38 | | | |
| 9/30/2017 | Southeastern Oklahoma State (7-4,7-4) | 30 | at | Northwestern Oklahoma State | 27 | | | |
| 10/7/2017 | Northwestern Oklahoma State | 38 | at | East Central (2-9,2-9) | 20 | | | |
| 10/14/2017 | Harding (11-4,8-3) | 34 | at | Northwestern Oklahoma State | 0 | | | |
| 10/21/2017 | Northwestern Oklahoma State | 10 | at | Arkansas Tech (8-4,8-3) | 66 | | | |
| 10/28/2017 | Northwestern Oklahoma State | 37 | at | Southern Nazarene (4-7,4-7) | 44 | | | |
| 11/4/2017 | Oklahoma Baptist (2-9,2-9) | 24 | at | Northwestern Oklahoma State | 31 | | | |
| 11/11/2017 | Southwestern Oklahoma State (3-8,3-8) | 7 | at | Northwestern Oklahoma State | 35 | | | |