| 8/31/2017 | Henderson State | 28 | at | Harding (11-4,8-3) | 20 | | | |
| 9/9/2017 | Arkansas Tech (8-4,8-3) | 26 | at | Henderson State | 3 | | | |
| 9/16/2017 | Northwestern Oklahoma State (5-6,5-6) | 36 | at | Henderson State | 30 | | | |
| 9/23/2017 | Henderson State | 37 | at | Southwestern Oklahoma State (3-8,3-8) | 14 | | | |
| 9/30/2017 | Southern Nazarene (4-7,4-7) | 42 | at | Henderson State | 24 | | | |
| 10/7/2017 | Henderson State | 14 | at | Oklahoma Baptist (2-9,2-9) | 13 | | | |
| 10/14/2017 | Henderson State | 21 | at | Southeastern Oklahoma State (7-4,7-4) | 20 | | | |
| 10/21/2017 | East Central (2-9,2-9) | 24 | at | Henderson State | 16 | | | |
| 10/28/2017 | Southern Arkansas (7-4,7-4) | 30 | at | Henderson State | 36 | | | |
| 11/4/2017 | Henderson State | 28 | at | Arkansas-Monticello (5-6,5-6) | 21 | | | |
| 11/11/2017 | Henderson State | 42 | at | Ouachita (9-3,9-2) | 49 | | | |