| 9/2/2017 | East Central | 55 | at | Oklahoma Baptist (2-9,2-9) | 34 | | | |
| 9/9/2017 | Southern Nazarene (4-7,4-7) | 33 | at | East Central | 30 | | | |
| 9/16/2017 | East Central | 7 | at | Arkansas-Monticello (5-6,5-6) | 49 | | | |
| 9/23/2017 | Ouachita (9-3,9-2) | 45 | at | East Central | 14 | | | |
| 9/30/2017 | East Central | 37 | at | Southwestern Oklahoma State (3-8,3-8) | 48 | | | |
| 10/7/2017 | Northwestern Oklahoma State (5-6,5-6) | 38 | at | East Central | 20 | | | |
| 10/14/2017 | Southern Arkansas (7-4,7-4) | 35 | at | East Central | 28 | | | |
| 10/21/2017 | East Central | 24 | at | Henderson State (6-5,6-5) | 16 | | | |
| 10/28/2017 | Arkansas Tech (8-4,8-3) | 38 | at | East Central | 10 | | | |
| 11/4/2017 | East Central | 13 | at | Harding (11-4,8-3) | 44 | | | |
| 11/11/2017 | East Central | 24 | at | Southeastern Oklahoma State (7-4,7-4) | 27 | | | |