| 9/3/2016 | Otterbein | 26 | at | Buffalo State (5-5) | 29 | at E8 | ||
| 9/17/2016 | Otterbein | 52 | at | Wilmington (0-10,0-9) | 7 | |||
| 9/24/2016 | Ohio Northern (5-5,5-4) | 16 | at | Otterbein | 10 | |||
| 10/1/2016 | Capital (4-6,4-5) | 42 | at | Otterbein | 41 | |||
| 10/8/2016 | Otterbein | 30 | at | Muskingum (4-6,3-6) | 17 | |||
| 10/15/2016 | Heidelberg (6-4,6-3) | 38 | at | Otterbein | 45 | |||
| 10/22/2016 | Otterbein | 33 | at | Baldwin-Wallace (3-7,2-7) | 30 | |||
| 10/29/2016 | Mount Union (12-2,8-1) | 66 | at | Otterbein | 7 | |||
| 11/5/2016 | Otterbein | 6 | at | John Carroll (12-2,9-0) | 49 | |||
| 11/12/2016 | Marietta (3-7,3-6) | 21 | at | Otterbein | 49 |
| vs Otterbein | vs Other Opponents | Otterbein compared to OOs | |
| Record: | 5-5 | 49-49 | |
| Points Scored: | 31.50 | 28.46 | -3.04 |
| Points Allowed: | 29.90 | 27.76 | 2.14 |
| Margin: | 1.60 | 0.70 | -0.90 |
| Total Points: | 61.40 | 56.22 | 5.18 |