| 9/3/2016 | Muskingum | 17 | at | Waynesburg (2-8) | 16 | at TPAC | ||
| 9/17/2016 | Capital (4-6,4-5) | 34 | at | Muskingum | 16 | |||
| 9/24/2016 | Marietta (3-7,3-6) | 10 | at | Muskingum | 28 | |||
| 10/1/2016 | Muskingum | 24 | at | Heidelberg (6-4,6-3) | 27 | |||
| 10/8/2016 | Otterbein (5-5,5-4) | 30 | at | Muskingum | 17 | |||
| 10/15/2016 | Muskingum | 14 | at | Baldwin-Wallace (3-7,2-7) | 13 | |||
| 10/22/2016 | Muskingum | 3 | at | Ohio Northern (5-5,5-4) | 44 | |||
| 10/29/2016 | John Carroll (12-2,9-0) | 31 | at | Muskingum | 3 | |||
| 11/5/2016 | Mount Union (12-2,8-1) | 44 | at | Muskingum | 0 | |||
| 11/12/2016 | Muskingum | 37 | at | Wilmington (0-10,0-9) | 7 |
| vs Muskingum | vs Other Opponents | Muskingum compared to OOs | |
| Record: | 6-4 | 46-52 | |
| Points Scored: | 25.60 | 29.38 | 3.78 |
| Points Allowed: | 15.90 | 30.00 | -14.10 |
| Margin: | 9.70 | -0.62 | -10.32 |
| Total Points: | 41.50 | 59.38 | -17.88 |