| 9/1/2016 | Northwest Missouri State | 41 | at | Emporia State (11-2,10-2) | 14 | | | |
| 9/8/2016 | Washburn (7-5,7-4) | 7 | at | Northwest Missouri State | 41 | | | |
| 9/17/2016 | Nebraska-Kearney (1-10,1-10) | 14 | at | Northwest Missouri State | 52 | | | |
| 9/24/2016 | Northwest Missouri State | 45 | at | Missouri Southern (2-9,2-9) | 21 | | | |
| 10/1/2016 | Central Missouri (9-3,9-2) | 17 | vs | Northwest Missouri State | 42 | | Kansas City MO | |
| 10/8/2016 | Northwest Missouri State | 56 | at | Central Oklahoma (3-8,3-8) | 10 | | | |
| 10/15/2016 | Northeastern State (2-9,2-9) | 29 | at | Northwest Missouri State | 74 | | | |
| 10/22/2016 | Northwest Missouri State | 47 | at | Lindenwood (3-8,3-8) | 12 | | | |
| 10/29/2016 | Pittsburg State (7-4,7-4) | 10 | at | Northwest Missouri State | 69 | | | |
| 11/5/2016 | Northwest Missouri State | 28 | at | Fort Hays State (8-4,7-4) | 7 | | | |
| 11/12/2016 | Missouri Western (4-7,4-7) | 3 | at | Northwest Missouri State | 44 | | | |
| 11/26/2016 | Emporia State (11-2,10-2) | 13 | at | Northwest Missouri State | 44 | | | |
| 12/3/2016 | Harding (13-1) | 0 | at | Northwest Missouri State | 35 | | D2 Quarterfinal | GAC |
| 12/10/2016 | Ferris State (12-3) | 20 | at | Northwest Missouri State | 35 | | D2 Semifinal | GLIAC |
| 12/17/2016 | North Alabama (11-2) | 3 | vs | Northwest Missouri State | 29 | | D2 Championship (Kansas City KS) | GSC |