| 9/1/2016 | Cheyney | 21 | at | Lincoln PA (1-9) | 20 | OT | at CIAA | |
| 9/10/2016 | California PA (11-1,11-0) | 79 | at | Cheyney | 3 | |||
| 9/17/2016 | Indiana PA (10-2,9-2) | 55 | at | Cheyney | 0 | |||
| 9/24/2016 | Bloomsburg (6-5,5-5) | 54 | at | Cheyney | 14 | |||
| 10/1/2016 | Cheyney | 12 | at | East Stroudsburg (4-7,3-7) | 54 | |||
| 10/8/2016 | Lock Haven (4-7,4-7) | 51 | at | Cheyney | 12 | |||
| 10/15/2016 | Cheyney | 0 | at | Shippensburg (7-4,6-4) | 76 | |||
| 10/22/2016 | Cheyney | 12 | at | West Chester (8-3,7-3) | 46 | |||
| 10/29/2016 | Millersville (2-9,1-9) | 34 | at | Cheyney | 6 | |||
| 11/5/2016 | Cheyney | 6 | at | Kutztown (7-4,7-3) | 32 | |||
| 11/12/2016 | Cheyney | 8 | at | Edinboro (9-2,8-2) | 66 |
| vs Cheyney | vs Other Opponents | Cheyney compared to OOs | |
| Record: | 10-1 | 59-52 | |
| Points Scored: | 51.55 | 30.46 | -21.09 |
| Points Allowed: | 8.55 | 29.82 | -21.27 |
| Margin: | 43.00 | 0.64 | -42.36 |
| Total Points: | 60.10 | 60.28 | -0.18 |